| Product name: |
MEK3 Rabbit pAb |
| Reactivity: |
Human, Mouse, Rat |
| Alternative Names: |
MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3 |
| Source: |
Rabbit |
| Dilutions: |
IHC 1:100-200 |
| Immunogen: |
Recombinant Protein |
| Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles. |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1mg/mL |
| Observed Band: |
34,39kDa |
| GeneID: |
5606 |
| Human Swiss-Prot No: |
P46734 |
| Cellular localization: |
Cytosol,Nucleus |
| Background: |
Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase . |
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