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EA347

規(guī)格：	價格：
50μL	￥1280.00
100μL	￥1980.00

下載說明 ①

Product name:	ATG4a Rabbit pAb
Reactivity:	Human, Mouse, Rat
Alternative Names:	Apg4a, Atg4al, Autl2,Cysteine protease ATG4A antibody
Source:	Rabbit
Dilutions:	IHC 1:100-200
Immunogen:	Recombinant Protein
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1mg/mL
Observed Band:	45kDa
GeneID:	115201
Human Swiss-Prot No:	Q8WYN0
Cellular localization:	Cytoplasm
Background:	Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).