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EM1083

規(guī)格：	價(jià)格：
50μL	￥1280.00
100μL	￥1980.00

下載說(shuō)明 ①

Product name:	IDE/Insulin Degrading Enzyme Mouse mAb
Reactivity:	Human
Alternative Names:	Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
Source:	Mouse
Dilutions:	WB 1:1,000 IHC 1:200
Immunogen:	Synthetic Peptide
Storage:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
Clonality:	Monoclonal
Isotype:	IgG1
Concentration:	1mg/mL
Observed Band:	118kDa
GeneID:	3416
Human Swiss-Prot No:	P14735
Cellular localization:	Cell membrane,?Cytoplasm,?Membrane,?Secreted
Background:	Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.